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Advanced generation e-cigarettes typically hold more amounts of e-liquid, produce more aerosols, and release more nicotine than previous generation e-cigarettes, allowing users to inhale more concentrated puff volumes in a short period of time, which indicates additional generation may pose a greater threat to health

Jaddoe and colleagues (2008) followed a cohort of 350 people enrolled at 519 years of age for at least 10 years with baseline and follow-up lipid measurements

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