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The yin and yang of dopamine Nicotine, like cocaine and heroin, is known to cause addiction by activating the bodys reward network: Nicotine binds to receptors on cells that release the neurotransmitter dopamine into the brain, where it affects everything from pain perception and mood to memory

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Department of Veterans Affairs

The most common side effects of varenicline include nausea, constipation, gas, vomiting, and trouble sleeping or vivid/strange dreams

Your body adjusting to no longer having nicotine is an unavoidable and often difficult part of quitting, especially if youve been smoking for a long time