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These findings shed light on mechanisms underlying 5FU resistance and propose a rational strategy for combination therapy in CRC, emphasizing the potential clinical benefit of targeting mitochondrial metabolism to overcome resistance and enhance patient outcomes

Konopka et al., 2020), which is linked to oxidative stress (Guerrero et al., 2019)

Despite these protective mechanisms, elevated serum B12 levels (hypercobalaminaemia) can occur and may indicate underlying health conditions rather than simple overconsumption

doi: 10.1016/j.nicl.2023.103503, 9 DuffyS

Melatonin alleviates glyphosate-induced testosterone synthesis inhibition via targeting mitochondrial function in roosters