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Traditional cigarettes are slowly being replaced by advanced heat-not-burn technology , which is a cleaner and more controlled way to enjoy tobacco

With repeated nicotine exposure, the GABA system becomes desensitized, leading to a shift in the action of nicotine to the DA neurons

This is an ongoing data collection by East Carolina University, led by Rutgers University, in an eastern NC site, and part of a multi-site National Institutes of Health study

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Previous research has indicated the importance of investigating gender difference in e-cigarette marketing strategies including innovations in product features (e.g., packaging and device design, appealing flavours), as they can influence gender difference in consumption