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Studies showed that the effect of gastrodin on depressive symptoms in single prolonged stress rats was related to the decreased expression of corticotropin releasing factor in paraventricular nucleus of the hypothalamus and central amygdala and the inhibition of neuron synthesis in locus ceruleus (Zhao R

R 2a is C 1 -C 6 alkyl, C 1 -C 6 alkyl-OR 5 , or C 1 -C 6 alkylC 3 -C 6 cycloalkyl

Methods This study was analytical observational with cross-sectional approach

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The Bottom Line The desire and need for better symptomatic therapies and certainly for a disease-modifying treatment for those living with PD is more than understandable