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Experimental evidence indicates that AS-IV downregulates advanced glycation end product (AGE) expression in hippocampal tissue in aging model rats, thereby inhibiting AGE-RAGE protein interactions on neurons and inflammatory cells, suppressing NF-B pathway activation, and reducing inflammation-related factors such as IL-6, IL-1, and TNF-

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In addition to negatively impacting the physical and mental health of the mother, HG can also affect the growth and health of the offspring