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The Short- and Long-Term Risks The short-term risks of smoking Ritalin can include: Euphoria followed by anxiety or panic Elevated blood pressure and rapid heartbeat Insomnia and restlessness Nose, throat, and lung irritation The long-term risks are even more alarming: Permanent lung damage and respiratory illness Cognitive decline, memory issues, and difficulty concentrating without the drug Severe mood swings, depression, or psychosis Heart problems, including heart attacks and stroke Development of stimulant use disorder The Centers for Disease Control and Prevention (CDC) has documented rising cases of stimulant-related hospitalizations, many involving non-traditional methods of use like smoking or injecting