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BPC-157, a 15-amino acid peptide derived from human gastric juice, shows remarkable potential for accelerating rib injury recovery based on preclinical research

Under unstressed conditions, three ER stress sensors (inositol-requiring enzyme 1 (IRE1), PKR like endoplasmic reticulum kinase (PERK), and activating transcription factor 6 (ATF6) (5962)) mainly bind to GRP78(78 kDa glucose-regulated protein), helping to keep it inactive

Pathobiol Aging Age Relat Dis , 2015, 5: 28776

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