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Overall, the aOoC approach holds great promise for ushering in a new era of precision medicine, enabling tailored therapeutic strategies and reducing the risks associated with generalized pre-clinical models

15 SerataM.YasudaE.SakoT

During strong autoimmune responses or central nervous system infections, immune cells like leukocytes, monocytes, and macrophages can cross the BBB using paracellular and transcellular routes[187]

Perilipin 1, a lipid droplet scaffold protein that coordinates interactions with ABHD5 and HSL Perilipin 1 (PLIN1), initially discovered by the group of Constantine Londos, is the major adipocyte perilipin/ADRP/TIP47 (PAT) protein (35) that functions as a scaffold to organized protein-protein interactions on the surface of LDs (36)

doi: 10.1055/a-2179-0809 68 ZhangCZhangLTianYGuanBLiS