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(iii) history of seizure disorder or gross neurological deficit

Interestingly, in one study, both GSH and GSSG worked in achieving the skin lightening effect, which appears to be very gradual and will take weeks to develop.23 The impact on pigmentation is transient, so you need to continue using glutathione to maintain the skin-whitening effect

[DOI] [PubMed] [Google Scholar] 79.Lu J, Vodnala SK, Gustavsson AL, Gustafsson TN, Sjoberg B, Johansson HA, Kumar S, Tjernberg A, Engman L, Rottenberg ME, Holmgren A

While it offers skin-brightening properties, it is not as potent a lightening agent as hydroquinone

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Mancini A., Meucci E., Milardi D., Giacchi E., Bianchi A., Pantano A.L., Mordente A., Martorana G.E., De Marinis L