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Following induction by LPS, CBD attenuated IL-8 and MCP-1 production but at the basal level, CBD induced the production of IL-8, CXCL1, Serpin E1, IL-6, IFN-y, MCP-1, RANTES, and TNF-, indicating that the effects of CBD may depend on the activation state [118] or anatomical location of the cells

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While consumers often perceive filtered cigarettes as safer, the ERS stated that filters provide no harm reduction and may encourage deeper inhalation of smoke into peripheral lung tissue