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Briefly, human in vitro systems do not reflect all aspects of cellular interaction and tissue organization, in vivo animal models do not necessarily reflect human biology in its finer details, and human clinical studies are hampered by time and cost constraints as well as accessibility to key biological samples (that are accessible in animal studies)

Therefore, EPA cannot assure these results are representative of all scenarios

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La loi de Financement de la Scurit Sociale du 23 dcembre 2022 prvoit, afin daider combler cette dette, une indexation de la hausse du prix du tabac sur linflation