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BiSpekDAb engineered by fusing anti-IL-23 domain antibody (VHH) and anti-TNF- domain antibody (VHH) to the 3rd domain of human serum albumin (3dHSA), using flexible linkers (GGGGS)

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Mice were anesthetized by inhaling a mixture of 1 L/min oxygen and 1%1.5% isoflurane via a mask, while maintaining normal respiration