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Larbre respiratoire nest mature quaux alentours de 20 ans et toute exposition prcoce ce que lon appelle l exposome (tabagisme, pollution, allergnes, etc.) compromet le futur respiratoire de lindividu, et peut dclencher des pathologies respiratoires de manire prcoce sur des terrains prdisposs

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In vitro treatment of THP-1 derived macrophages with sodium arsenite (up to 8 M for 48 h) promoted differentiation into M2 macrophages, inducing secretion of fibrogenic cytokines via upregulation of the miRNA miR-21 (204)