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A publication was excluded if it did not report IQOS-specific data, reported data unrelated to the topic (toxicity and health impact), or if the study was retracted or did not report original data

Some researchers claim that more prolonged exposure to smoke (e.g., 40 years, a half pack per day) poses a higher risk than shorter periods (10 years with two packs per day) even though the number of pack years is the same in both cases

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