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9 -THC produces hypoactivity, hypothermia as well as spatial and verbal memory impairment via CB1 [61]

One of the ways the FDA combats youth tobacco use is through its compliance and enforcement efforts, including encouraging retailer compliance and taking action when violations occur.

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Notably, in both the US/Canada and the United Kingdom, more than 82% of participants reported using the highest JUUL nicotine concentration available (18 mg/mL in the United Kingdom and 59 mg/mL in the US/Canada)