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The virus can be spread only through contact with an HIV-positive persons bodily fluids (blood, semen, vaginal or rectal fluids, or breast milk)

The whitish middle of a canker sore is made of fibrin (a protein involved in blood clotting) and inflammatory cells

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Ethics statement The studies involving human participants were reviewed and approved by Institutional Review Boards of the Second Affiliated Hospital of Zhejiang University School of Medicine