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doi: 10.1530/JME-17-0311 38 SabatiniDM

26 KO was confirmed by Western blot and led to changes in KRAS and phospho-protein levels (pERK, pAKT, and/or pSTAT3) with individual patterns in different cell lines, indicating potential activation of different compensatory signaling pathways (Supplementary Fig

This dietary pattern not only expands adipose tissue mass but also fundamentally alters its secretory profile, increasing the release of the very adipokines and exosomes that drive joint destruction