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Exactly one day after being diagnosed with bilateral breast cancer in August 2012, Notaro took the stage for a standup routine in Los Angeles and told the audience point-blank, "I have cancer." It became one of the most poignant, riveting, hilarious shows in recent comedy memory, described by fellow standups with reverent terms like "masterful" and "transcendent." It brought Louis C.K

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Effect of exposure to e-cigarettes with salt vs free-base nicotine on the appeal and sensory experience of vaping