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It is in any individuals absolute best interest to never smoke or at least quit smoking, if they are current smokers, says Anthony W

I've added a bit of post to the final image, a vignette, High Pass filter and some other tricks I usually do to finish an image (PLUS users check "SMOKE_LAYERED_POST.PSD")

Additive effects: CNS depressants (alcohol, benzodiazepines, opioids) can increase sedation and impair judgment

In general, any changes to the immune and inflammatory protein milieu are concerning, as increased inflammation is associated with poor oral health and decreased levels indicates subjects are at risk for infections

One of my favorites for fall and winter