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Biochem Biophys Res Commun 450:12611265 van Willigenburg H, de Keizer PLJ, de Bruin RWF (2018) Cellular senescence as a therapeutic target to improve renal transplantation outcome

Downstream signaling through the phosphoinositide 3-kinase (PI3K)-AKT (also known as protein kinase B) pathway, IGF1 signaling mediates an increase in survival of newly born neurons via the promotion of anabolic activity and glucose utilization, and the inhibition of glycogen synthase kinase 3b (GSK3b)

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