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Cathepsin B deteriorates diabetic cardiomyopathy induced by streptozotocin via promoting NLRP3-mediated pyroptosis

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In a recent systematic review and meta-analysis of five randomized controlled trials and five observational studies aimed at comparing pregnancy outcomes between users and non-users of castor oil for labor induction, castor oil users were significantly more likely to give birth within 24 h than non-users (relative risk, 3.46

This synergistic effect of positive activation and negative regulation constitutes a complete inflammatory initiation-activation-abatement regulatory loop