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But apart from that, it is clear that alcohol played an important role then

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Abstract Smokeless tobacco (SLT) use has many oral effects including oral cancer, leukoplakia and erythroplakia, oral submucous fibrosis (if mixed with areca nut), loss of periodontal support (recession) and staining of teeth and composite restorations

Exposing mice for 4 months to active (La Maestra et al., 2011) or passive (Moreno-Gonzalez et al., 2013) cigarette smoke induces oxidative stress, DNA damage and neuropathology in mice