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From 2008 to 2010, menthol cigarette use among young adult current smokers (ages 18 to 25) was 47.3% among Hispanics

doi: 10.4049/jimmunol.0802204

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The results showed that Sp1 knockdown reduced the inhibitory effect of the miR-125a-5p inhibitor on MLE-12 cell senescence, the expression levels of Sp1 and SIRT1 were reduced, the level of HIF-1 acetylation increased, and the cellular senescence markers p21 and p27 were up-regulated