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3 Despite a historical decline, CO remains one of the leading causes of poisoning-related emergency department (ED) visits, with 50,000 cases annually in the United States

This imbalance means that the population is informed only of the potential risks associated with e-cigarettes, without knowing that there is also a whole body of literature showing that these devices have positive effects on the health of smokers

Detailed characteristics of each study are provided in Table 1

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