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For instance, the prolonged administration of MTX often leads to side effects
Ginsburg and Hensler, 2022)
The metabolites and the pathways to which they belong have been grouped into five groups viz.-(i) Central Carbon metabolism (glce, glcc, g6p, f6p, f16bp, gap, dhap, 1,3bpg, 3pg, akg), (ii) Amino Acid metabolism (3php, pser, ser, gly, cyse, cys, cysL, glute, glut), (iii) Thiol metabolism (glucys, gsh, gssg), (iv) h2o2 production and metabolism (O2(ex), O2, oxrad, h2o2) (v) Redox metabolism (nadph, nadp+)
: 59.40 30 : 5