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However, in later stages, after withdrawal of sympathetic influence, vagally mediated bradycardia can occur.CNS stimulation is characterized by tremors, confusion, and headache, and in extreme cases, seizures and coma.Fasciculations and twitching due to skeletal muscle stimulation often go unnoticed due to rapidly developing receptor desensitization and motor inactivation
Cytochrome P450 CYP2B6 is the main isoenzyme involved in bupropion metabolism 19 , and this study indicated that participants with mutant AA genotype had significantly higher success rates compared to those with AG or GG genotypes