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The major ferroptosis-related pathways influenced by polysaccharides are the SLC7A11/GSH/GPX4 pathway, Keap1/Nrf2/HO-1 pathway, NCOA4-mediated ferritinophagy pathway, ACSL4-mediated lipid peroxidation pathway, and their upstream signal such as PI3K/Akt, Wnt/-catenin, p53, and the AMPK/BECN1 autophagy pathway

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Discussion The pathways for glutathione synthesis, recycling and metabolism are well established (Figure 6)

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