(PubMed) Maitra I, Serbinova E, Tritschler HJ, Packer L
Glutathione ng vai tr quan trng trong vic sn xut t bo bch cu, gip tng cng kh nng min dch ca c th, chng li cc bnh nhim trng nh cm cm, vim phi, vv Glutathione cn c tc dng h tr gii c gan, bo v gan khi tc hi ca ru bia, thuc l v cc cht c hi khc
Our group has recently invented a molecular combination (cARLA) synergistically targeting signaling pathways related to BBB maturation that elevated the barrier tightness and other BBB-specific properties in several BBB culture models including human stem cell-based ones [40]
SIRT3 overexpression in HSCs improves the function of distant tissues through myeloid cells Adoptive transfer experiments demonstrated that splenocytes from aged mice were sufficient to induce systemic senescence in young recipients, despite the short-lived nature of donor immune cells, supporting the concept that relatively small numbers of functionally altered immune cells can exert broad physiological effects through systemic signaling mechanisms, without requiring long-term engraftment 52
In murine models, FMT has shown therapeutic benefits by restoring Firmicutes species and attenuating systemic inflammation post-RT
