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Discard vial 28 days after first use

Comprehensive literature searches were performed in PubMed, Web of Science, and Google Scholar (title search only) up to January 31, 2025

Carrillo-Vico A, Lardone PJ, Naji L et al (2005) Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects

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In the case of troglitazone (an antidiabetic drug, voluntarily withdrawn from the market by the licence holder in 2000), it was reported that 1.95% of patients treated with troglitazone in clinical trials developed eleva-tions of aminotransferases that were greater than three times the upper limit of normal