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Beyond simple chelation, GSH also acts as a molecular chaperone, facilitating the delivery of Cu to specific copper chaperones (e.g., ATOX1) and supporting their function, particularly in copper export [107]

Similarly, endometriosis in both patients and animal models is associated with elevated ROS in follicular fluid, NLRP3 inflammasome activation, GC pyroptosis, and loss of follicular integrity, collectively impairing oocyte maturation and fertility [71]

Conclusion and future perspective Immunometabolism has emerged as a major and popular area of research in immunological disease, focusing on cellular metabolism and metabolic programs of specific cells, have advanced our understanding of pathogenesis and novel therapeutic targets

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