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Through ubiquitin-dependent or ubiquitin-independent receptor-mediated pathways, damaged mitochondria are enclosed in autophagosomes and transported to lysosomes for degradation and recycling, which is important for basal mitochondrial turnover and the maintenance of physiological conditions [2, 3] (Fig

Nave CD4 + T cells (0.4 10 6 ) were cultured in RPMI-1640 medium supplemented with 10% FBS (Gibco, CA, USA), 2 mM glutamine, 1% penicillin streptomycin (Gibco, CA, USA), 10 mmol/L N-2-hydroxyethylpiperazine-N-2-ethanesulfonic acid (HEPES, Gibco, CA, USA), and 55 mmol/L 2-mercaptoethanol (Gibco, CA, USA) in 24-well plates

For instance, a 2022 study by Sushanthi et al

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either way, he is clearly in more conciliatory mood today