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Thanks go to Katya Knyazeva for contributing to this article

In a validation cohort derived from the Genetic Epidemiology Study of Lung Adenocarcinoma in Taiwan, the YAP1 R331W allele frequency was 1.1% in patients with LUAD versus 0.18% in individuals without cancer, translating into an OR of 5.9 after adjusting for age, sex and smoking status 214

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For those concerned about lung health, the best course of action is to quit using all forms of nicotine

Previous real-world studies required smokers to transfer their cigarettes into plain packs created by the researchers, a limitation recognized by the authors [3]