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Pre-treatment of human primary chondrocytes with alogliptin for 24 h (25 and 50 M) prevented the degradation of type II collagen and aggrecan dose-dependently

This suggests different inflammatory-metabolic associations among different RA models, which could explain the various cardiac and vascular alterations observed

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Naini AE, Sadeghi M, Mortazavi M, Moghadasi M, Harandi AA