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Evidence to date is primarily derived from preclinical and animal models, with emerging case series data

It helps restore the gut lining often damaged by antibiotics, mold toxins, or persistent infections

Claudin-2 increases Na + and water flux across the pore pathway but larger molecules are unable to traverse claudin-2 channels

It is defined by two or three amino acids anchoring the peptides in the discrete pockets of the peptide binding groove of the cognate HLA molecule, and one or two TCR-specific contact residues, while tolerating a broad amino acid diversity at other positions of the antigenic peptides

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