Short-term refrigeration (28C) is acceptable during active use but not recommended for long-term storage
10.1016/j.neuropharm.2012.03.002 Neuropharmacology
This is not necessarily dangerous, but requires understanding that blood sugar effects may be unpredictable
Eur J Nutr 46:20412 Papakostas GI, Shelton RC, Zajecka JM, Etemad B, Rickels K, Clain A, Baer L, Dalton ED, Sacco GR, Schoenfeld D, Pencina M, Meisner A, Bottiglieri T, Nelson E, Mischoulon D, Alpert JE, Barbee JG, Zisook S, Fava M (2012) l-Methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials
The puffy white powder can be stored at room temperature until youre ready to reconstitute it with bacteriostatic water