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The observed increase in oxytocin receptor expression in the anterior cingulate cortex of MIA mice suggests a potential neurobiological mechanism underlying these effects [1]

A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily

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research shows no additional benefit above 1 mg daily Important: Doses above 1 mg (1,000 mcg) daily showed no additional metabolic benefits in clinical research

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