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Hemodynamic Consequences Increased pulmonary vascular resistance (PVR): Mechanical obstruction + hypoxia-mediated vasoconstriction raises afterload on the thin-walled RV

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A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation