what is glutathione conjugation

what is glutathione conjugation Don't Lose Your (War)head: Structure–Activity Relationships of Covalent Warheads as Substrates for GST-Catalyzed Glutathione Conjugation Services - BOC

Name: what is glutathione conjugation Don't Lose Your (War)head: Structure–Activity Relationships of Covalent Warheads as Substrates for GST-Catalyzed Glutathione Conjugation Services - BOC
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[Abstract]2025 Sep 18;188(19):5194-5211.e16

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Sperandio S, de Belle I, Bredesen DE

It has been postulated before that either residue Sec498 hTrxR1 or residue Cys497 hTrxR1 attacks the intra-molecular hTrx1-disulphide (Cys32 hTrx1 , Cys35 hTrx1 ), forming an inter-molecular disulphide bond between hTrx1 and hTrxR1 during catalysis 23