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All 100 units (1 mL) are drawn with an insulin syringe, plus any remaining solution

These include appetite suppression, induction of satiety, reduced caloric intake, suppression of gastric acid secretion and delayed gastric emptying

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They follow disc injury in animal models 22 , although the small and young animals used in such experiments are not always a reliable guide to disc degeneration in humans 22,23 , for whom no equivalent data are available

However, PGPIPN treatment significantly diminished these changes in PGPIPN 1, 2 and 3 groups (Figure 8A and 8B)