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Additionally, glutathione can modulate the immune response, which is crucial for controlling HSV-1 infections

High extracellular concentrations of glutamate, another raw material for glutathione synthesis, can inhibit system ( SLC7A11 ) and induce iron-dependent non-apoptotic cell death, which may explain the toxic effect of excessive glutamate accumulation in the nervous system (Yang and Stockwell, 2016

The negative association between GSH/GSSG, and oxidative protein and DNA damage suggest that decreased glutathione redox capacity in the autism brain may have functional consequence in terms of increased mitochondrial superoxide production and a chronic inflammatory state

More recent studies state that females with autism report lifetime sensory symptoms and fewer communication problems than males