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Carcinogenesis (2004) 25:8390

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Signs of infection: Increasing pain and warmth Pus or drainage Fever Red streaks extending from affected area Infections can develop in damaged skin

Electrophysiological evidence for a role of nitric oxide in prolonged chemical nociception in the rat

Under physiological conditions, high levels of ROS are counterbalanced by antioxidants, which competently maintain a delicate redox balance by donating their electrons to the ROS and thus interrupting further intake of electrons from surrounding compartments [37]