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But the mechanism isn't appetite suppression or calorie burning

Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies

High concentrations or chronic administration of glucocorticoids promote apoptosis of immune cells, including T cells, macrophages, dendritic cells, and eosinophils in mice and humans (89), whereas lower concentrations and shorter exposure windows exhibit more nuanced effects on inflammation and immunity

TNF- plays an important roles in many processes, such as cell survival, apoptosis, necrosis, and intercellular communication 27

Cell Stem Cell 21 , 806818.e5 (2017)