71 These changes also contribute to a higher rate of other substance use disorders among people who use tobacco during adolescence, sometimes referred to as a "gateway" effect
however, there are very few studies which characterize aerosols from smoking marijuana joints
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During chronic inflammation, myofibroblasts are characterized by high matrix remodeling activity and the ability to generate abundant ECM components (e.g., -SMA, collagen, and MMPs) [44, 45], leading to the thickening and sclerosis of lung tissue, ultimately culminating in PF (Fig
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