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The switching group had lower levels of 8-epi-PGF 2 compared to those who had continued smoking: a 6.23% at 3 months into the study, and 6.8% at 6 months

This includes devices, nicotine salt, and freebase e-liquids, as well as DIY products such as base liquids, longfills, and flavor concentrates

The planned interim analysis, conducted when 124 participants had been randomised, suggested 1122 additional participants needed to be randomised for sufficient power to detect an effect

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