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Iron deficiency enhances eryptosis primarily through oxidative stress amplification and calcium (Ca 2+ ) dyshomeostasis

In the case of redox stress, two molecules of GSH reduce one molecule of hydrogen peroxide in the presence of glutathione peroxidases, generating one molecule of glutathione disulfide (GSSG), an oxidized form of GSH, and two molecules of water [122, 123]

10.3969/j.issn.1672-5123.2006.03.020 69 LiX.JingN.LiuX