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Each combination of amino acids produces unique and very specific functions

Claire MC, Nagashima K, Harbaugh SW, Harbaugh JW, Olivero OA, Divi RL, Albert PS, Poirier MC (2004) Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed Transplacentally to zidovudine plus lamivudine

These inflammatory stressors are considered to induce disease-associated glial phenotypes (Pape et al., 2019)

The program has grown more sophisticated over time

Early therapeutic interventions for both the neuroinflammatory and neurodegenerative aspects of the disease, used in tandem, will likely be key to further therapeutic advances and the ultimate goal of true remission of the disease