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As an initial test of the ability of 6-AH family members to alter HGF-dependent cellular activity we evaluated the capacity of several members of the family to modify the proliferative activity of Madin-Darby canine kidney (MDCK) cells, a standard cellular model for investigating the HGF/Met system (Stella and Comoglio, 1999)

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Lyophilized peptides, in particular, can last for years if stored properly

1419), (Diagen, Ljubljana, Slovenia) dissolved in saline, was used in all experiments

Nasal sprays offer a non-invasive alternative with rapid absorption and potential for direct-to-brain pathways, but the total absorbed dose might be slightly lower