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Rat-derived tendon fibroblast studies measured migration, survival and signalling endpoints
Of note, these patients are also at high risk for cardiovascular disease
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In a rat wound model and in rat dermal fibroblast cultures, GHK-Cu increased type I collagen and glycosaminoglycan production and modulated the expression of the dermal proteoglycans decorin and biglycan
By sequestering actin and releasing it to fuel lamellipodia extension, TB-500 accelerates the physical migration of keratinocytes and fibroblasts into the repair zone, increasing migration speed by 2-3 fold
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