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The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

von Kanel R, Mausbach BT, Dimsdale JE, et al

If you accidentally make contact with a non-sterile surface, discard that needle or syringe and use a fresh one from sealed packaging

GLP-1 receptor agonists caused thyroid C-cell tumors in rodent studies, and while human cases are rare, the FDA requires a black-box warning

Before you begin this medication, it can be useful to review the following with a healthcare provider: CagriSema is an investigational treatment that should be used only under a clinicians supervision, as complete data on its long-term safety are not yet available